Model membrane studies related to ionic transport in biological systems

by Sol S. Nelson

Publisher: U.S. Dept. of the Interior; for sale by the Supt. of Docs., U.S. Govt. Print. Off. in [Washington]

Written in English
Published: Pages: 88 Downloads: 181
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  • Membranes (Technology),
  • Biological transport.

Edition Notes

Statementby S. S. Nelson and I. Blei for Office of Saline Water.
SeriesResearch and development progress report, no. 221
ContributionsBlei, Ira, 1931- joint author., Melpar, inc.
LC ClassificationsTD478 .U5 no. 221
The Physical Object
Paginationviii, 88 p.
Number of Pages88
ID Numbers
Open LibraryOL5561120M
LC Control Number67060826

  Ionic transport processes; in electrochemistry and membrane science. Kontturi, Kyosti et al. Oxford U. Press pages $ Hardcover QD Electrode reactions and membrane processes may seem to be widely disparate that they do share transport phenomena as .   Additionally, a brief overview is given of surfactant-like effects in biological systems, technical applications of surfactants that involve membrane interactions, and surfactant-based protocols to study biological by:   The insufficient understanding of unintended biological impacts from nanomaterials (NMs) represents a serious impediment to their use for scientific, technological, and medical applications. While previous studies have focused on understanding nanotoxicity effects mostly resulting from cellular internalization, recent work indicates that NMs may interfere with transmembrane transport Cited by: 2. Indiana State University Biochemistry. This note covers the following topics: Basic Chemistry of Amino Acids, Carbohydrates, Lipids and Nucleic Acids, Ionic Equilibria, Biological Membranes and Transport, Protein Structure and Analysis, Hemoglobin and Myoglobin, Enzyme Kinetics, Vitamins and Minerals, Glycolysis: Regulating Blood Glucose, Fructose Metabolism, Ethanol Metabolism Non-Glucose.

Medical Biochemistry Page Indiana University. This note covers the following topics: Basic Chemistry of Amino Acids, Carbohydrates, Lipids and Nucleic Acids, Ionic Equilibria, Biological Membranes and Transport, Protein Structure and Analysis, Hemoglobin and Myoglobin, Enzyme Kinetics, Vitamins and Minerals, Glycolysis: Regulating Blood Glucose, Fructose Metabolism, Ethanol Metabolism Non. `The main topic covered by this book, ionic transport, is of technological importance in relation to the current interest in membrane technology, for instance for developments in fuel cells. The complexity of these problems requires a fundamental approach and understanding of the basic processes taking place.5/5(1). ISBN: OCLC Number: Notes: Proceedings of the Second International Conference on Water and Ions in Biological Systems, held Sept. , , in Bucharest, Romania, under the auspices of UNESCO, the Union of Societies of Medical Sciences in the Socialist Republic of Romania, the Romanian Biophysical Society, and the Academy of Medical Sciences, in .   National Institute of Standards and Technology (NIST). (, December 8). Scientists channel graphene to understand filtration, ion transport into cells. ScienceDaily.

The cell membrane (also known as the plasma membrane (PM) or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space) which protects the cell from its environment. Cell membrane consists of a lipid bilayer, including cholesterols (a lipid component) that sit. Modelling biological systems is a significant task of systems biology and mathematical biology. Computational systems biology aims to develop and use efficient algorithms, data structures, visualization and communication tools with the goal of computer modelling of biological systems. It involves the use of computer simulations of biological systems, including cellular subsystems (such . Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore. Their functions include establishing a resting membrane potential, shaping action potentials and other electrical signals by gating the flow of ions across the cell membrane, controlling the flow of ions across secretory and epithelial cells, and regulating cell volume.   These notes are in part based on a course for advanced students in the applications of stochastic processes held in at the University of Konstanz. These notes contain the results of re­ cent studies on the stochastic description of ion transport through biological membranes. In Author: Eckart Frehland.

Model membrane studies related to ionic transport in biological systems by Sol S. Nelson Download PDF EPUB FB2

Additional Physical Format: Online version: Nelson, Sol S., Model membrane studies related to ionic transport in biological systems. [Washington] U.S. Dept. By b. (Sol S.) Nelson, joint author. Ira Blei, United States. Office of Saline Water. and Incorporated.

Melpar. Topics include membranes of high electrochemical activity in physicochemical and model studies of biological interest and membrane resting potential. The selection is a vital reference for readers interested in ion transport across membranes.

In this chapter, we study simple models related to ion transport through a membrane. We draw a close analogy to electronic circuit theory and describe the ion transport similar to a simple RC-network.

We study the Goldman–Hodgkin–Katz model for a steady state with more than one ionic Author: Philipp O. Scherer, Sighart F. Fischer. In this study, we provide a foundational model of ion transport processes in the intracellular and extracellular compartments of neurons at the nanoscale.

There are two different kinds of ionic transport processes: (i) ionic transport across the neuronal membrane (trans-membrane), and (ii) ionic transport along both the intracellular and extracellular surfaces of the by: 4.

Abstract. Biological membranes have been an active area of research within the biomolecular simulation community for two decades or so now. Thus there is a rich body of literature describing computational studies of membrane proteins, lipids, drugs that interact with membranes, and the interactions between these different types of molecule.

A simple theory for multi-ionic transport, nonequilibrium water dissociation, and space-charge effects in bipolar membranes is developed on the basis of some of the concepts used in the solid. 1 Ion Transport Through Cell Membrane Channels Jan Gomułkiewicz 1, Jacek Mi ękisz 2, and Stanisław Mi ękisz 3 1 Institute of Physics, Wrocław Technical University; 2 Institute of Applied Mathematics and Mechanics, Warsaw University; 3 Department of Biophysics, Medical University of Wrocław Abstract.

We discuss various models of ion transport through cell membrane : Jan Gomulkiewicz, Jacek Miekisz, Stanislaw Miekisz. The complexity of biological membranes has motivated the development of a wide variety of simpler model systems whose size, geometry, and composition can be tailored with great precision.

Approaches highlighted in this review are illustrated in Figure 1 including vesicles, supported bilayers, and hybrid membrane systems. These have been used to Cited by: Nanodiscs are a new class of model membranes that are being used to solubilize and study a range of integral membrane proteins and membrane-associated proteins.

Ion Transport through Biological Membranes An Integrated Theoretical Approach. Authors (view affiliations) decrementing action potential as a signaling mechanism for the long range trans­ mission of information in the nervous system, and to gain some in­ sight into the gross behaviour of neurons.

The detailed analysis of Hodgkin and. Introduction to Biological Membranes: Composition, Structure and Function, Second Edition is a greatly expanded revision of the first edition that integrates many aspects of complex biological membrane functions with their composition and structure.

A single membrane is composed of hundreds of proteins and thousands of lipids, all in constant flux. transport, selectivity, and partitioning of chemical and biological species. Such systems draw advantage from enhanced surface area-to-volume (SA/V) scal-ing that leads to reduced diffusion time scales in contrast to conventional microfluidic systems for transport toward surfaces and rapid kinetics.

The ability to capture and manipulate. Dear Colleagues, The scope of this Special Issue involves a large number of topics in the field of membrane science. We welcome papers that include or report on the following: experimental studies and mathematical modeling providing new knowledge of the mechanisms of ion and molecule transportation in artificial and living systems; a description of ion and molecule transportation through.

Current mainstream neural computing is based on the electricity model proposed by Hodgkin and Huxley inthe core of which is ion passive transmembrane transport controlled by ion channels. However, studies on the evolutionary history of ion channels have shown that some neuronal ion channels predate the neurons.

Thus, to deepen our understanding of neuronal activities, ion channel models Author: Vincent Qiqian Wang, Shenquan Liu. solutions of high ionic strength, Different transport systems in biological membranes What are the types of passive transport. •Two types of passive transport: With the help of a simple labelled diagram describe the “Fluid mosaic model” of membrane structure.

Briefly describe the two types of passive transport across Size: KB. Ion Transport in Membranes: Incorporation of Biological Ion-Translocating Proteins in Model Membrane Systems Annual Review of Physiology Vol.

(Volume publication date March )Cited by: Dear Colleagues, The scope of this Special Issue involves a large number of topics in the field of membrane science. We welcome papers reporting: Experimental studies and mathematical modeling providing new knowledge on the mechanisms of ion and molecule transport in artificial and living systems; The description of ion and molecule transport through all kinds of membranes, biological.

In cellular biology, membrane transport refers to the collection of mechanisms that regulate the passage of solutes such as ions and small molecules through biological membranes, which are lipid bilayers that contain proteins embedded in them.

The regulation of passage through the membrane is due to selective membrane permeability - a characteristic of biological membranes which allows. Ion transport is crucial for biological systems and membrane-based technology. Atomic-thick two-dimensional materials, especially graphene oxide (GO), have emerged as Cited by: The carbon-nanotube model membranes used in our study result in systems that are small compared to biological membrane channels and thus computationally relatively inexpensive.

The small size and relative simplicity of our system allow us to investigate the thermodynamics and kinetics of ion translocation through a hydrophobic pore with explicit-solvent MD by:   Equations of Membrane Biophysics provides an introduction to the relevant principles of thermodynamics, kinetics, electricity, surface chemistry, electrochemistry, and other mathematical theorems so that the quantitative aspects of membrane phenomena in model and biological systems could be Edition: 1.

Ion transport of multi-ionic solutions through layered electrolyte and polyelectrolyte structures are relevant in a large variety of technical systems such as micro and nanofluidic devices Cited by:   Transport may involve the incorporation of biological molecules and the discharge of waste products that are necessary for normal function.

Membrane transport refers to the movement of particles (solute) across or through a membranous barrier. 2 These membranous barriers, in the case of the cell for example, consist of a phospholipid bilayer. Correlating the structure and action of biological molecules requires knowledge of the corresponding relation between structure and energy.

Probably the most important factors in such a structure– energy correlation are associated with electrostatic by: Ion channels are biological nanotubes that are formed by membrane proteins.

Because ion channels regulate all electrical activities in living cells, understanding their mechanisms at a molecular level is a fundamental problem in biology. This book deals with recent breakthroughs in ion-channel. The behaviors of individual molecules are much more closely related to physical laws than behaviors of complex biological systems or organisms.

Every molecular biologist I have ever met agrees that vitalism is inappropriate in his or her science: explanations of the behavior of proteins and nucleic acids should be found in the laws of physics. The response indicates that substance L most likely crosses the membrane by active transport.

The response indicates that the cells maintain an intracellular concentration of mM, which is always greater than the concentration of substance L in the culture medium.

Biochemistry,, Biochemistry,, File Size: KB. Bob Eisenberg Ionic Channels Journal of Membrane Biology, 3 In this quite limited sense, then, vitalism is an appropriate part of biology.

Physical laws undoubtedly govern the behavior of these complex systems, as well as governing the behavior of their elements, but, taken as a whole, biological systems, and organisms, often.

Ionic Transport Processes: In Electrochemistry and Membrane Science - Kindle edition by Kontturi, Kyösti, Murtomäki, Lasse, Manzanares, José A. Download it once and read it on your Kindle device, PC, phones or tablets.

Use features like bookmarks, note taking and highlighting while reading Ionic Transport Processes: In Electrochemistry and Membrane Science.5/5(1).The Fluid Mosaic Model of the Cell Membrane Take a look at the components of the cell membrane and a model to illustrate its structure.

Passive Transport in Cells: Simple and Facilitated Diffusion.ADVERTISEMENTS: The following points highlight the five processes involved in transport of molecules across cell membrane. The processes are: 1.

Passive Diffusion 2. Facilitated Diffusion 3. Active Transport 4. Group Translocation 5. Ion Transport through Ionophores. Process # 1. Passive Diffusion: By passive diffusion, molecules move across the membrane without interacting with any specific.